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Less common diabetes

Type 3c diabetes (diabetes of the exocrine pancreas)

Type 3c diabetes is caused by damage to the pancreas rather than by insulin resistance. The same damage usually affects digestive enzymes too, so glucose and nutrition have to be managed together.

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Understanding the condition

Type 3c diabetes happens when the pancreas is damaged and cannot make enough insulin. Doctors also call it diabetes of the exocrine pancreas or pancreatogenic diabetes.1 The common causes are chronic pancreatitis, surgery that removes part or all of the pancreas, pancreatic cancer, cystic fibrosis and haemochromatosis.12 Because the pancreas does two jobs, the same damage often reduces the digestive enzymes it releases, a problem called pancreatic exocrine insufficiency.1

Type 3c is frequently recorded as type 2 diabetes, because the label is less well known and is not always used.2 If you have had a pancreatic problem, it is worth asking your doctor to check for type 3c.2 The clues are digestive symptoms such as oily stools, weight loss and tummy pain, and insulin that is needed earlier than you would expect in type 2.2 Getting the label right matters, because the pancreas also makes glucagon, the hormone that helps stop glucose falling too low. For that reason, hypoglycaemia in type 3c needs a plan built with a team that has seen it before.1

Insulin is needed by many people with type 3c, and tablets are enough for some, but that decision belongs to your GP or specialist.1 Enzyme replacement capsules, taken with meals and snacks, are prescribed when digestion is affected, and doses are set with a dietitian.34 Fat soluble vitamins A, D, E and K are checked and replaced when they are low.4 At PDC Health Hub a Credentialled Diabetes Educator and an Accredited Practising Dietitian usually work on the same case, because food, enzymes and insulin all move together.

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Type 3c diabetes (diabetes of the exocrine pancreas)

What to look out for, and how we help

Symptoms are a guide, not a diagnosis. Your GP confirms the diagnosis; our team helps you manage it day to day.

What you might notice

  • Thirst, passing more urine than usual, tiredness and blurred vision, the usual signs of high glucose.
  • Weight loss you did not plan, even when you are eating.
  • Oily, pale or floating stools, diarrhoea, wind and bloating, which point to low digestive enzymes.
  • Pain in the upper tummy that can spread to the back, either constant or in episodes.
  • Low glucose episodes that are hard to lift, or that keep happening after insulin doses.
  • Call 000 for an ambulance if a low glucose episode is severe, meaning one you cannot treat yourself, or where the person is unconscious or fitting. Also call 000 if high glucose comes with vomiting, deep rapid breathing, a fruity smell on the breath, drowsiness or confusion, which can mean diabetic ketoacidosis. Go to the nearest emergency department for sudden severe upper tummy pain, especially with vomiting, fever or a racing heart, because those symptoms can also look like a heart attack.

How our team helps

  • A Credentialled Diabetes Educator consultation that treats type 3c as its own condition, not as type 2 with extra steps.
  • Insulin starts and adjustment within your GP or specialist plan, with attention to how much food you are actually absorbing.
  • An Accredited Practising Dietitian to work out enzyme timing and doses with meals and snacks, within the plan your prescriber has set, and to protect weight and muscle.
  • Continuous glucose monitoring to find the lows that are easy to miss when glucagon is affected.
  • Insulin pump and hybrid closed loop starts and troubleshooting where your prescriber has recommended them.
  • Pharmacist medication support, including how to take enzyme capsules and what to do when a dose is missed.

Your PDC care team

The teams and services that most often support people with this condition. They work from one shared plan, and one GP referral reaches all of them.

Allied health teams

Diabetes Education
Diabetes Education
Allied health team
Diabetes Education
Expert guidance from Credentialled Diabetes Educators for all types of diabetes including Type 1 diabetes, Type 2 diabetes, gestational diabetes, and all diabetes technology.
Read more

Dietitian
Dietitian
Allied health team
Dietitian
Personalised nutrition advice from Accredited Practising Dietitians to help manage blood glucose levels, weight management and overall nutritional health.
Read more

Pharmacy
Pharmacy
Allied health team
Pharmacy
On-site pharmacy services providing expert medication management, diabetes supplies, and health consultations.
Read more

Related services

Related conditions

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Sources and clinical review

This page follows Australian information on type 3c diabetes from Diabetes Victoria, the Australasian Pancreatic Club guidelines on pancreatic enzyme replacement therapy and the Pancare Foundation enzyme dosing guide, and uses Diabetes UK guidance on misclassification and treatment order where Australian consumer material is silent. Emergency advice for low glucose, for diabetic ketoacidosis and for sudden severe pancreatic pain follows the NDSS and Healthdirect.

  1. Diabetes Victoria. Type 3c diabetes, undated. https://www.diabetesvic.org.au/about-diabetes/other-diabetes-types/type-3c-diabetes/
  2. Diabetes UK. Type 3c diabetes, undated. https://www.diabetes.org.uk/diabetes-the-basics/type-3c-diabetes
  3. Pancare Foundation. Pancreatic enzyme replacement therapy: a guide for clinicians, 2022. https://pancare.org.au/wp-content/uploads/Pancare_PERT-Guide_A5_WEB.pdf
  4. Nikfarjam M, Wilson JS, Smith RC, on behalf of the Australasian Pancreatic Club PERT Guidelines Working Group. Diagnosis and management of pancreatic exocrine insufficiency. Medical Journal of Australia, 2017. https://www.mja.com.au/journal/2017/207/4/diagnosis-and-management-pancreatic-exocrine-insufficiency
  5. Healthdirect. Diabetic ketoacidosis (DKA), 2024. https://www.healthdirect.gov.au/diabetic-ketoacidosis
  6. National Diabetes Services Scheme. Hypoglycaemia (low blood glucose), version 6.0.0, 2026. https://www.ndss.com.au/living-with-diabetes/management-and-care/hypoglycaemia/
  7. Healthdirect. Pancreatitis, 2024. https://www.healthdirect.gov.au/pancreatitis
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Common questions

Is type 3c diabetes the same as type 2?
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No. Type 2 diabetes is mainly about insulin resistance. Type 3c starts with damage to the pancreas itself, so less insulin is made, and the digestive side of the pancreas is often affected as well. The treatment order is different as a result.

Why was I told I had type 2 first?
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Type 3c is less well recognised and the label is not always used, so adults who develop diabetes are often recorded as type 2 by default. If you have had pancreatitis, pancreatic surgery, pancreatic cancer, cystic fibrosis or haemochromatosis, it is worth asking your doctor to look at this specifically.

Why do I need enzyme capsules as well as diabetes treatment?
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The pancreas makes digestive enzymes as well as insulin, and the same damage can reduce both. Without enough enzymes, fat is not digested properly, which causes oily stools, weight loss and low levels of vitamins A, D, E and K. Enzyme capsules are taken with meals and snacks, and a dietitian helps match the dose to what you eat.

Why am I getting more lows than other people on insulin?
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The pancreas also makes glucagon, which normally helps stop glucose falling too low. When that is affected, lows can be harder to correct. This is one reason type 3c is managed with an individual plan rather than standard settings, and why continuous glucose monitoring is often useful.

Who looks after this, and where does PDC fit?
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Your GP, and often a gastroenterologist, endocrinologist or surgeon, make the diagnosis and prescribe. PDC Health Hub provides the diabetes education, dietetics, pump and CGM work and pharmacist support that sit underneath that plan. We see people in clinic across Western Australia and by telehealth.

Not sure where to start?

Tell us what is going on and we will point you to the right discipline, or to more than one. Most people start with a single appointment and leave with a plan the rest of the team can see.

Or go straight to a service

Phone (08) 6110 0570 · Medicare, NDIS, DVA and private options across our services

For GPs and health professionals

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